Through a grant from the National Cancer Institute, Professor of Biology Nancy Krucher, PhD, Anastasiia Vaska 男女操逼视频软件24, and Michael Ferretti 男女操逼视频软件24 are exploring how a new cancer drug could help tackle the resistance patients can develop to ongoing treatments.

Nancy Krucher
Biography
Faculty Bio
I have worked and published in cancer research for 30 years. My decision to pursue graduate studies in biomedical research was the direct result of working in a research laboratory studying muscular dystrophy for one and a half years as an undergraduate back in the 1980s when few students had that opportunity. I was 男女操逼视频软件渉ooked男女操逼视频软件 on research as an undergraduate and now love to share that excitement for research with the current generation of students. In fact, my interaction and mentorship of undergraduate students in the research laboratory is the most important and rewarding part of my work as a professor.
Education
MS
PhD, Clarkson University, Potsdam, 1995
Cellular Biology
BS, Syracuse University, Syracuse NY, 1988
Molecular and Cellular Biology
Research and Creative Works
Research Interest
We are currently investigating targeted therapy resistance in cancer. Therapies designed to reduce resistance in melanoma include the use of metabolism inhibitors in combination with currently used clinical drugs such as B-RAF inhibitors.
Grants, Sponsored Research and Contracts
Targeting ATP-citrate lyase (ACLY) to overcome therapy resistance in breast cancer and melanoma.
Krucher, N. A. December 2022 - November 2025. NIH, Federal. Funded.
Courses Taught
Past Courses
BIO 101: General Biology I
BIO 231: Genetics
BIO 292: Bio Lbrtry Rsrch Training
BIO 292: Bio Lbrtry Rsrch Trng
BIO 327: Cellular Biochemistry
BIO 335: Molecular & Cellular Biology
BIO 375: Advanced Cell Biology
BIO 395: Independent Study in Biology
BIO 396: Guided Study in Biology
BIO 480: Research in Biology
BIO 481: Research in Biology II
BIO 491: Internship in Biology
BMB 710: Research I
BMB 711: Research II
CHE 329: Adv Biochemistry Laboratory
CHE 480: Research in Chemistry
ENS 600: Grad Ens - Independent Study
ENS 690: Tpc: Molecular & Cellular Bio
ENS 699: Special Topics in Env Science
Publications and Presentations
Publications
Combined inhibition of ACLY and CDK4/6 reduces cancer cell growth and invasion.
Velez, B. C., Petrella, C. P., DiSalvo, K. H., Cheng, K., Kravtsov, R., Krasniqi, D. & Krucher, N. A. (2023). Oncology reports. Vol 49 (Issue 2)
Structure男女操逼视频软件揳ctivity relationships and transcriptomic analysis of hypoxia-inducible factor prolyl hydroxylase inhibitors
Poloznikov, A. A., Nikulim, S. V., Hushpulian, D. M., Khristichenko, A. Y., Osipyants, A. I., Asachenko, A. F., Shurupova, O. V., Savin, S. S., Lee, S. H., Gaisina, I. N., Thatcher, G. J., Narciso, A., Chang, E. P., Kazakov, S. V., Krucher, N. A., Tishkov, V. I., Thomas, B. & Gazaryan, I. (2022). Antioxidants. Vol 11 , pages 220.
Targeting retinoblastoma protein phosphorylation in combination with EGFR inhibition in pancreatic cancer cells.
Thomas, N. A., Abraham, R. G., Dedi, B. & Krucher, N. A. (2019). International journal of oncology. Vol 54 (Issue 2) , pages 527-536.
Dephosphorylation of the Retinoblastoma protein (Rb) inhibits cancer cell EMT via Zeb.
Krucher, N. A., Egger, J. V., Lane, M. V., Antonucci, L. A. & Dedi, B. (2016). Cancer biology & therapy. Vol 17 (Issue 11) , pages 1197-1205.
Related News and Stories
Biology professor Nancy Krucher, PhD, understands the transformative power of research. She男女操逼视频软件檚 a pioneer in the fight against breast cancer, and she男女操逼视频软件檚 just received a three-year $400,241 grant from the National Cancer Institute through the National Institutes of Health to study new methods to combat cancer cell development of resistance to targeted treatments.
男女操逼视频软件 Professor of Biology Nancy Krucher, PhD, has received a three-year $400,241 grant from the National Cancer Institute (NCI) through the National Institutes of Health (NIH) to study new methods to combat cancer cell development of resistance to targeted treatments.